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Psilocybin mushrooms, often referred to as “magic mushrooms,” are fungi containing the psychoactive compounds psilocybin and psilocin. Specifically, these substances act as partial agonists at serotonin receptors in the brain, which alters sensory perception, mood, and cognitive processes. Consequently, users may experience profound shifts in consciousness and visual hallucinations. Furthermore, recent clinical research in the USA, UK, and Australia has investigated their therapeutic potential for treating treatment-resistant depression and end-of-life anxiety. However, it is essential to recognize that these substances remain illegal in many jurisdictions. Moreover, ingestion carries significant risks, including unpredictable psychological reactions and toxic misidentification of wild mushroom species.-Psilocybin mushroom effects on the brain